The research for development of polyvalent lived vaccine based on current varicella vaccine

Varicella Vaccine

to an affected household member. In healthy children, varicella usually does not cause serious complications. However, immunocompromised children and otherwise healthy adults are at increased risk for life-threatening complications of varicella such as pneumonia, encephalitis, and disseminated infection. Although <10% of all cases of varicella occur in adults, this age group accounts for 25-30%...

Current tuberculosis vaccine development.

Information derived from the complete genome sequence of Mycobacterium tuberculosis makes it possible to develop a range of new vaccine candidates. Strategies currently under investigation include construction of whole cell live attenuated mycobacterial vaccines, as well as the use of individual antigens delivered by a variety of subunit vaccination procedures. Fundamental questions associated ...

Impact of vaccine cost and information about complications of varicella on parental decision regarding varicella vaccine.

BACKGROUND The influence of providing information about complications of disease and vaccine cost on parental decision to vaccinate against varicella was assessed. METHOD During telephone interviews of 330 parents of infants aged 9 months, parents were asked if they would agree to have their child vaccinated and were presented information first about varicella complications and then about cos...

Nontyphoidal salmonella disease: Current status of vaccine research and development.

Among more than 2500 nontyphoidal Salmonella enterica (NTS) serovars, S. enterica serovar Typhimurium and S. enterica serovar Enteritidis account for approximately fifty percent of all human isolates of NTS reported globally. The global incidence of NTS gastroenteritis in 2010 was estimated to be 93 million cases, approximately 80 million of which were contracted via food-borne transmission. It...

Production and standardization of polyvalent Clostridium perfringens vaccine in Iran